منابع مشابه
Metabolomics integrated elementary flux mode analysis in large metabolic networks
Elementary flux modes (EFMs) are non-decomposable steady-state pathways in metabolic networks. They characterize phenotypes, quantify robustness or identify engineering targets. An EFM analysis (EFMA) is currently restricted to medium-scale models, as the number of EFMs explodes with the network's size. However, many topologically feasible EFMs are biologically irrelevant. We present thermodyna...
متن کاملPrincipal Typing in Elementary Affine Logic
Elementary Affine Logic (EAL) is a variant of the Linear Logic characterizing the computational power of the elementary bounded Turing machines. The EAL Type Inference problem is the problem of automatically assign to terms of λ-calculus EAL formulas as types. The problem is solved by showing that every λ-term which is typeable has a finite set of principal typing schemata, from which all and o...
متن کاملPrincipal Dynamic Mode Analysis of the Hodgkin-Huxley Equations
We develop an autoregressive model framework based on the concept of Principal Dynamic Modes (PDMs) for the process of action potential (AP) generation in the excitable neuronal membrane described by the Hodgkin-Huxley (H-H) equations. The model's exogenous input is injected current, and whenever the membrane potential output exceeds a specified threshold, it is fed back as a second input. The ...
متن کاملDynamic Modeling of the Electromyographic and Masticatory Force Relation Through Adaptive Neuro-Fuzzy Inference System Principal Dynamic Mode Analysis
Introduction: Researchers have employed surface electromyography (EMG) to study the human masticatory system and the relationship between the activity of masticatory muscles and the mechanical features of mastication. This relationship has several applications in food texture analysis, control of prosthetic limbs, rehabilitation, and teleoperated robots. Materials and Methods: In this paper, w...
متن کاملIn silico prediction of elementary mode fluxes
How perturbations such as enzyme deletions or changes in nutrient composition affect th e d istribution o f f luxes in a metabolic s ystem remains poorly understood. Elementary modes are a mathematical concept enabling the decomposition of complex metabolic networks into minimal chains of reactions that operate at steady state. They were proven to be a useful tool for analyzing the range of pos...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular BioSystems
سال: 2016
ISSN: 1742-206X,1742-2051
DOI: 10.1039/c5mb00828j